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Santa Ana, CA (May 4, 2025) – A traffic collision resulting in injuries occurred in the Pico-Lowell neighborhood of Santa Ana. The crash was reported at approximately 12:50 a.m. near 1246 Highland St, prompting a response from local emergency personnel.

First responders, including paramedics, assessed and treated individuals hurt in the crash. At least one person sustained a variety of injuries, though it remains unclear whether any victims were transported to a medical facility. The number of vehicles involved and the specific events leading to the incident have not yet been released.

Santa Ana Fire and Rescue arrived quickly to secure the scene and assist the injured. The residential street was partially closed during the initial response, and traffic was temporarily affected while crews cleared the area and began their investigation.

The cause of the crash is under active investigation by local law enforcement. Officers are gathering statements from witnesses and reviewing any nearby surveillance footage that may help determine how the crash occurred.

Our thoughts are with those injured in this incident, and we hope for their full and speedy recovery.

Neighborhood Street Risks and Late-Night Collisions in Santa Ana

The Pico-Lowell neighborhood, just northwest of downtown Santa Ana, consists primarily of residential streets with limited visibility and multiple cross-streets. While not a major arterial road, Highland St still sees late-night traffic, particularly from residents and local service vehicles.

Santa Ana, part of the greater Orange County region, continues to face a notable number of nighttime collisions. The California Office of Traffic Safety reports that late-hour crashes often involve factors such as speeding, alcohol use, or driver fatigue. In 2024, the city recorded hundreds of injury-related accidents, with residential areas like Pico-Lowell seeing a share of those incidents.

These crashes can be especially dangerous when drivers are less alert and road lighting is limited. Motorists are urged to reduce speeds on residential streets and remain vigilant for other vehicles, pedestrians, or sudden obstructions.

In areas with limited traffic control, defensive driving and heightened awareness can help prevent serious outcomes during overnight hours.

If you or someone you know has been injured in a crash, reach out to Local Accident Reports for assistance.